From a Protein Name to a Druggability Estimation in just 4 Clicks
8. Juni 2018
From a Protein Name to a Druggability Estimation in just 4 Clicks
We are happy to announce the next release of our ProteinsPlus web server. One of the major achievements is its combination with the powerful text search capabilities from the RCSB protein data bank (PDB) provided as RESTful service. Now. free text search with advanced options is directly available from ProteinsPlus. An overview of the resulting protein structures is displayed with the most important facts available at one glimpse. Beside the structural aspects, such as experimental technique, resolution. or R-Free, the containing ligands are shown as a preview to allow the identification of interesting protein-ligand complexes. Further filter criteria are at hand to narrow down the results and help you find the structure you want. Now, starting from a protein name, the definition and analysis of active sites, protonation and even ensemble generation for flexible docking or mutation analysis is just a few clicks away.
ProteinsPlus is a free service supported by de.NBI - German Network for Bioinformatics Infrastructure. Several sofware tools behind ProteinsPlus are also available for local use as part of our NAOMI Chembio Suite. Get the basics of ProteinsPlus from our open access NAR 2017 paper.